NEOADJUVANT INTRATUMORAL IMMUNOTHERAPY WITH COWPEA MOSAIC VIRUS INDUCES LOCAL AND SYSTEMIC ANTITUMOR EFFICACY IN CANINE MAMMARY CANCER PATIENTS

Neoadjuvant Intratumoral Immunotherapy with Cowpea Mosaic Virus Induces Local and Systemic Antitumor Efficacy in Canine Mammary Cancer Patients

The lack of optimal models to evaluate novel agents is delaying the development of effective immunotherapies against human breast cancer (BC).In this prospective open label study, we applied neoadjuvant intratumoral immunotherapy with empty cowpea mosaic virus-like particles (eCPMV) to 11 companion dogs diagnosed with canine mammary cancer (CMC), a

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A sweeping algorithm of unstructured elements in discontinuous spectral element method for thermal radiation in irregular multidimensional geometries

The discontinuous spectral element method (DSEM) coupled with an element-by-element sweeping strategy is proposed as NEFF N50 KI5852SF0G Integrated 50/50 Fridge Freezer a solution to the radiative transfer equation (RTE) for participating media in irregular geometries.In the solving processing, a spatial domain of RTE is discretized by unstructured

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The combined effect of Covid-19 and neighbourhood deprivation on two dimensions of subjective well-being: Empirical evidence from England.

ObjectivesThe Covid-19 pandemic is hitting societies hard, and people living in disadvantaged circumstances are among the most affected.We investigate the combined effects of the Covid-19 crisis and living in a deprived neighbourhood on two dimensions of subjective well-being: hedonic (i.e.mental health) and evaluative (i.e.life satisfaction) subje

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